Crystallization and preliminary X-ray diffraction analysis of a eumenine mastoparan toxin: a new class of mast-cell degranulating peptide in the waspvenom
F. Canduri et al., Crystallization and preliminary X-ray diffraction analysis of a eumenine mastoparan toxin: a new class of mast-cell degranulating peptide in the waspvenom, ACT CRYST D, 56, 2000, pp. 1434-1436
Mastoparans are tetradecapeptides found to be the major component of vespid
venoms. A mastoparan toxin isolated from the venom of Anterhynchium flavom
arginatum micado has been crystallized and X-ray diffraction data collected
to 2.7 Angstrom resolution using a synchrotron-radiation source. Crystals
were determined to belong to the space group P6(2)22 (P6(4)22). This is the
first mastoparan to be crystallized and will provide further insights into
the conformational significance of mastoparan toxins with respect to their
potency and activity in G-protein regulation.