Acute annular outer retinopathy: Report of four cases

PURPOSE: To describe the clinical findings and course in four patients with acute annular outer retinopathy. METHODS: Four patients were evaluated during the course of acute annular ou ter retinopathy, and the historical and clinical findings were retrospectiv ely collected. RESULTS: Four healthy patients developed the acute onset of visual field lo ss associated with a localized, white annular outer retinopathy, All patien ts were caucasian; two were women, aged 29 and 32 years, and two were men, aged 71 and 79 years. The mean follow-up was 3.9 years (range, 1 to 6 years ). On presentation, four eyes had an irregular, incomplete, peripapillary, annular band of gray-white, deep retinal opacification with visual acuities that varied from 20/25 without foveal involvement to counting fingers with foveal involvement, Laboratory serologies were unremarkable. Two patients did not receive any treatment, and two received varying courses of oral cor ticosteroids with subjective improve ment, Of the four eyes, two eyes devel oped ophthalmoscopic sequelae, one eye did not, and one had evidence of ret inal pigment epithelial damage and narrowing of the retinal vessels on pres entation. CONCLUSIONS: These four cases of acute annular outer retinopathy expand our knowledge of this disorder. Acute annular outer retinopathy may be a disti nct entity or it may represent a variant of acute zonal occult outer retino pathy. As more cases are recognized, the characteristic features of the dis ease spectrum, the etiology, and treatment options may be better elucidated . (C) 2000 by Elsevier Science Inc. All rights reserved.