Localized bullous pemphigoid induced by thermal burn.

Background. Induced bullous pemphigoid is known to be triggered by drugs an d some physical agents. Six cases of bullous pemphigoid induced by thermal burns have been reported since 1991 Case report. We observed a bullous eruption around thermal burns of the lef t leg in a 89 year-old woman. Bullous pemphigoid was diagnosed by histologi cal and immunohistochemical findings with a subepidermal blister and linear IgG and C-3 deposition at the dermal-epidermal junction. Indirect immunofl uorescence was negative. The eruption rapidly resolved with topical steroid s. Discussion. We describe a bullous pemphigoid induced by a thermal burn. Thi s case is original because the eruption was localized only around the site of the burn and healed with topical steroids. In the literature, there are 6 other cases reported but only one localized. We discuss the hypothesis of asymptomatic bullous pemphigoid exacerbated by presentation of bullous pem phigoid antigen by thermal burns or self immunization against antigens alte red by burns.