Homozygous Factor V Leiden mutation in a woman with multiple adverse pregnancy outcomes

Authors
Pauer, HU Neesen, J Schloesser, M Hinney, B Pauer, HU
Citation
Hu. Pauer et al., Homozygous Factor V Leiden mutation in a woman with multiple adverse pregnancy outcomes, ARCH GYN OB, 264(3), 2000, pp. 164-165
Citations number
14
Categorie Soggetti
Reproductive Medicine
Journal title
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
ISSN journal
09320067 → ACNP
Volume
264
Issue
3
Year of publication
2000
Pages
164 - 165
Database
ISI
SICI code
0932-0067(200011)264:3<164:HFVLMI>2.0.ZU;2-O
Abstract
We report a case with one intrauterine fetal death (IUFD) at 32 weeks of ge station, one premature delivery at the same week, and one abortion of unkno wn etiology at 12 weeks of gestation. We discuss that the presence of homoz ygosity for Factor V Leiden may be associated with placental insufficiency in this woman. Application of anticoagulant therapy may have been beneficia l in her current pregnancy.