We report a case of ovarian cancer with metastasis to both breasts and axil
lary lymph nodes and the vaginal cuff. A 41-year-old previously hysterectom
ized women presented with pelvic mass and malignant pleural effusion. Durin
g the courses of chemotherapy; bilateral breast nodules, and bilateral axil
lary lymphadenopathies and a nodule in the vaginal cuff were identified. Th
e biopsy of both breasts, axillary lymph nodes and the nodule in the vagina
l cuff revealed papillary serous cystadenocarcinoma. Immunohistochemical st
aining of breast specimens were positive for ovarian tumor marker CA-125.