Avian somatotrophs: differentiation, morphology, distribution, and regulation

Growth hormone (GH) is primarily synthesized, stored, and released by pitui tary somatotrophs. These cells comprise a highly labile population that con tinuously undergoes proliferation, differentiation, and morphogenesis in re sponse to changing physiological stimuli. They are also functionally and mo rphologically heterogeneous with distinct spatial and temporal distribution within the pituitary gland. The characteristics of these cells are discuss ed in this brief review.