Temperature and solvent effects on enzyme stereoselectivity: inversion temperature in kinetic resolutions with lipases

Authors
Cainelli, G De Matteis, V Galletti, P Giacomini, D Orioli, P
Citation
G. Cainelli et al., Temperature and solvent effects on enzyme stereoselectivity: inversion temperature in kinetic resolutions with lipases, CHEM COMMUN, (23), 2000, pp. 2351-2352
Citations number
29
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
23
Year of publication
2000
Pages
2351 - 2352
Database
ISI
SICI code
1359-7345(2000):23<2351:TASEOE>2.0.ZU;2-6
Abstract
Eyring plots of lnE vs. 1/T show inversion temperature in kinetic resolutio n by lipases, demonstrating that clustering effects in the substrate solvat ion manage the enzymatic selectivity.