Phosphine-phosphite, a new class of auxiliaries in highly active and enantioselective hydrogenation

Authors
Pamies, O Dieguez, M Net, G Ruiz, A Claver, C
Citation
O. Pamies et al., Phosphine-phosphite, a new class of auxiliaries in highly active and enantioselective hydrogenation, CHEM COMMUN, (23), 2000, pp. 2383-2384
Citations number
26
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
23
Year of publication
2000
Pages
2383 - 2384
Database
ISI
SICI code
1359-7345(2000):23<2383:PANCOA>2.0.ZU;2-M
Abstract
Excellent enantioselectivities (ee > 99%) and good activities (TOF > 1200 h (-1)) are achieved under mild reaction conditions in the Rh-catalyzed hydro genation of alpha,beta -unsaturated carboxylic acid derivatives with the fi rst family of phosphine-phosphite ligands containing a sugar backbone; thes e ligands are better than their diphosphine, diphosphite and phosphinite an alogues.