Citation
Jj. Hu et al., Studies on the reaction between N-phosphoryl amino acids and ribonucleosides, CHEM J CH U, 21(11), 2000, pp. 1667-1670
Citations number
23
Categorie Soggetti
Chemistry
Journal title
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
ISSN journal
02510790
→ ACNP
Volume
21
Issue
11
Year of publication
2000
Pages
1667 - 1670
Database
ISI
SICI code
0251-0790(200011)21:11<1667:SOTRBN>2.0.ZU;2-7
Abstract
The interaction between N-phosphoryl amino acids and nucleosides in aqueous
medium was studied and the products were analyzed on the basis of HPLC and
LC-MS-MS techniques. The results demonstrated that peptides and oligonucle
otides were simultaneously formed. Different selectivities were observed be
tween the reaction of various kinds of N-phosphoryl amino acids and differe
nt nucleosides, The results gave some clue for the chemical characteristics
of the origin of primordial genetic code.