Introduction: The aim of this paper was to describe a rare gastrointestinal
motility disorder caused by vascular compression of the duodenum. Patients
: The authors present two patients with vomiting and severe weight loss. Di
agnostic evaluation revealed superior mesenteric artery syndrome. Methods:
After frustrane treatment with i.v. infusions, surgical intervention with l
aterolateral duodenojejunostomy or Roux-en-y reconstruction for restoration
of the intestinal passage was performed. Results: Following initial recove
ry, the first patient showed permanent anorexia. Psychosocial evaluation re
vealed a severe pathological mother-child relationship. Intensive psycholog
ical treatment finally achieved definite weight gain and complete recovery
in this patient. The second case subsequently gained weight without psychol
ogical evaluation. Conclusion: The authors review the literature, pointing
out the anatomy of the duodenojejunal angle, the etiology, and the predispo
sing factors, as well as diagnostic and therapeutic strategies.