Failure of pentavalent antimony in visceral leishmaniasis in India: Reportfrom the center of the Indian epidemic

Authors
Sundar, S More, DK Singh, MK Singh, VP Sharma, S Makharia, A Kumar, PCK Murray, HW
Citation
S. Sundar et al., Failure of pentavalent antimony in visceral leishmaniasis in India: Reportfrom the center of the Indian epidemic, CLIN INF D, 31(4), 2000, pp. 1104-1107
Citations number
19
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
31
Issue
4
Year of publication
2000
Pages
1104 - 1107
Database
ISI
SICI code
1058-4838(200010)31:4<1104:FOPAIV>2.0.ZU;2-R
Abstract
In India, 320 patients with visceral leishmaniasis (209 in the state of Bih ar and 11 in the neighboring state of Uttar Pradesh) received identical pen tavalent antimony (Sb) treatment. Sb induced long-term cure in 35% (95% con fidence interval [CI], 28-42%) of those in Bihar versus 86% (95% CI, 79%-93 %) of those in Uttar Pradesh, In Bihar, the center of the Indian epidemic, traditional Sb treatment should be abandoned.