Emerging concepts In metabolic abnormalities associated with coronary artery disease

To an increasing degree, cardiology and endocrinology are finding a broaden ing interface. There is little doubt that atherosclerosis is in many ways a metabolic disorder, just as it is becoming increasingly clear that diabete s is a vascular disease, Framing such notions is evidence of diabetes as a risk equivalent for coronary disease, and clinical cardiovascular trials de monstrate the impact of altering lipid metabolism. Although the focus has b een on statins and LDL, data continues to emerge for other therapies for tr iglycerides and HDL, These issues are discussed, as are future directions f or metabolic therapeutic interventions for Vascular disease. (C) 2000 Lippi ncott Williams & Wilkins, Inc.