Background and objective. Malignant melanomas on sun-exposed skin are often
poorly circumscribed and thus recur frequently. The aim of our clinical tr
ial was to compare conventional to a modified micrographic surgery of prima
ry melanoma.
Patients/Methods. 28 patients with in-situ (n=7) and invasive (n=21) melano
ma were treated with conventional surgical excision with wide margins; eigh
t of these patients developed a local recurrence. In comparison, 20 patient
s with primary in-situ (n=7) and invasive (n=13) melanoma as well as four p
atients with recurrence after conventional surgery underwent modified micro
graphic surgery with delayed closure of the wound.
Results. Paraffin specimens of the margins revealed in half of the patients
remnants of melanoma although excision was extended to non-lesional skin.
Within a mean followup period of 21.3 months, none of our patients treated
by modified surgery developed a recurrence.
Conclusions. Local recurrencies of melanoma on sun exposed skin may be avoi
ded by means of a modified micrographic surgery using permanent histologic
sections.