Bilateral segmental neurofibromatosis mimicking epidermal nevus

Neurofibromatosis is a neuroectodermal systemic disease. A ra re variant of this condition is bilateral segmental neurofibromatosis. A 29-year-old man presented with bilateral papillomatous plaques in the lumbar dermatomes. C linically, the lesions were very similar to an epidermal nevus but histolog ic examination revealed superficial neurofibromas. Family history, ophthalm ologic and neurologic investigations were unremarkable. The unusual morphol ogic presentation of bilateral segmental neurofibromas in this case points to the wide clinical spectrum of the disease and the significance of histol ogic examination in systematic nevoid lesions.