Quantitative EEG methods and measures in human psychopharmacological research

The quantitative analysis of electroencephalographic (EEG) signals is an es tablished methodology for objectively describing the central impact of drug s administered to human subjects. This paper outlays the essential objectiv es and findings of this electrophysiologic measurement model of drug action and addresses the subject, recording, analytical and statistical standards which are required to ensure valid pharmaco-EEG profiling. Copyright (C) 2 000 John Wiley & Sons, Ltd.