A comparative study on serum levels of testosterone and SHBG in carcinomasof breast and uterine cervix

Authors
Ray, A Naik, SLD Katiyar, S Kumar, A Murthy, NS Sharma, S Bahadur, AK Pasha, ST Husain, SA Sharma, BK
Citation
A. Ray et al., A comparative study on serum levels of testosterone and SHBG in carcinomasof breast and uterine cervix, I J BIOCH B, 37(4), 2000, pp. 210-215
Citations number
39
Categorie Soggetti
Biochemistry & Biophysics
Journal title
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
ISSN journal
03011208 → ACNP
Volume
37
Issue
4
Year of publication
2000
Pages
210 - 215
Database
ISI
SICI code
0301-1208(200008)37:4<210:ACSOSL>2.0.ZU;2-B
Abstract
Serum levels of testosterone and sex-hormone binding globulin (SHBG) were m easured in 31 patients with breast carcinoma and 33 patients with carcinoma of the uterine cervix along with 30 healthy (control) women. Amongst the p atients of breast cancer, significantly higher level of testosterone and a low level of SHBG were found in comparison with the other two groups. The s tudy has revealed that testosterone and SHBG may have an indirect role in b reast cancer, probably through their influences on the amount of bioavailab le estrogen.