A case of isolated ACTH deficiency presenting with hypercalcaemia

Authors
Wong, RKM Gregory, R Lo, TCN
Citation
Rkm. Wong et al., A case of isolated ACTH deficiency presenting with hypercalcaemia, INT J CL PR, 54(9), 2000, pp. 623-624
Citations number
10
Categorie Soggetti
General & Internal Medicine
Journal title
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
ISSN journal
13685031 → ACNP
Volume
54
Issue
9
Year of publication
2000
Pages
623 - 624
Database
ISI
SICI code
1368-5031(200011)54:9<623:ACOIAD>2.0.ZU;2-0
Abstract
A 76-year-old man presented with a subacute history of weight loss, malaise and anorexia. Laboratory investigations revealed serially increasing hyper calcaemia, correlating with deterioration in his clinical status. He was su bsequently shown to have hypocortisolaemia, which improved with the adminis tration of intravenous steroids. Subsequent biochemical testing revealed th e endocrinological defect to be one of isolated ACTH deficiency, which, unl ike Addison's disease, does not classically include hypercalcaemia in its p resentation.