Studying metabolic, endocrine, and gastrointestinal (MEG) disorders in drug
abuse and HIV infection is important. Equally important, however, are the
tools we use to assess these disorders. Assessment of nutritional status ma
y include any combination of biochemical and body composition measurements,
dietary intake assessment, and metabolic studies, Each method has its stre
ngths and weaknesses and there is no perfect tool. When assessing nutrition
al status in injection drug users (IDU) and in HIV-infected people, the dec
ision on which method or methods to use becomes even more complex. A review
of studies reported during the XII World Conference on AIDS reveals that o
f 64 abstracts on the topic of nutrition in HIV-infected adults, only 11 as
sessed diet, 41 assessed anthropometry, and 23 assessed some form of bioche
mical measure. The most commonly reported methods for dietary intake includ
ed 24-hour recalls, food records, and food frequencies. The commonest metho
ds used for measuring body composition included height, weight, bioimpedanc
e, and dual-energy x-ray absorptiometry (DEXA). Biochemical measurements in
cluded various blood nutrients, lipids, and albumin. Methods varied greatly
between studies, and caution should be taken when trying to compare result
s across studies, especially among those using different methods. Currently
, few studies deal with the development of methods that can be used for res
earch in HIV-infected and IDU populations. We need to work toward better to
ols in dietary intake assessment, body composition, and biochemical measure
ments, especially methods that will allow us to track changes in nutritiona
l status over time.