The purpose of this investigation was to compare anxiety and depression in
Taiwanese cancer patients with and without pain. In 1998, a convenience sam
ple of 203 hospitalized cancer patients, 77 with pain and 126 without pain,
were assessed for anxiety and depression using the Hospital Anxiety and De
pression Scale (HADS). Disease-related factors such as performance status,
disease stage and perceived treatment effect were also assessed and control
led for their effect on anxiety and depression. The prevalence of both anxi
ety and depression in the pain group was significantly higher than that for
the pain-free group. After controlling the effect of disease-related facto
rs, patients' pain status had a significant effect on depression but not on
anxiety. Patients with pain had more depressive symptoms than patients wit
hout pain. Cancer patients' anxiety can be predicted significantly by funct
ional status and perceived treatment effect. In addition to pain status, ca
ncer patients' depression can be predicted by their functional status.