Isolation and structure of pulcherrimine, a novel bitter-tasting amino acid, from the sea urchin (Hemicentrotus pulcherrimus) ovaries

Authors
Murata, Y Sata, NU
Citation
Y. Murata et Nu. Sata, Isolation and structure of pulcherrimine, a novel bitter-tasting amino acid, from the sea urchin (Hemicentrotus pulcherrimus) ovaries, J AGR FOOD, 48(11), 2000, pp. 5557-5560
Citations number
18
Categorie Soggetti
Agricultural Chemistry","Chemistry & Analysis
Journal title
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
ISSN journal
00218561 → ACNP
Volume
48
Issue
11
Year of publication
2000
Pages
5557 - 5560
Database
ISI
SICI code
0021-8561(200011)48:11<5557:IASOPA>2.0.ZU;2-V
Abstract
A novel sulfur-containing amino acid, pulcherrimine, has been isolated as a bitter principle from ovaries of the sea urchin Hemicentrotus pulcherrimus . The structure was elucidated as 4-(2'-carboxy-2'-hydroxy-ethylthio)-2-pip eridinecarboxylic acid by spectroscopic and chemical methods. Absolute ster eochemistry was determined by NOE experiments and chiral HPLC analysis. Pul cherrimine exhibited bitterness with a threshold value of 0.306 mM.