Long-range hole transport in DNA

Authors
Wessely, S Giese, B
Citation
S. Wessely et B. Giese, Long-range hole transport in DNA, J BIO STRUC, 2000, pp. 293-295
Citations number
19
Categorie Soggetti
Biochemistry & Biophysics
Journal title
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
ISSN journal
07391102 → ACNP
Year of publication
2000
Pages
293 - 295
Database
ISI
SICI code
0739-1102(2000):S2<293:LHTID>2.0.ZU;2-G
Abstract
A guanine radical cation (G(+.)) was site-selectively generated in double-s tranded DNA and the hole transport from G(+.) to a GGG unit in G(+.)(TTG)(N )GG sites (N=1-4) was analyzed. The overall rate of the charge transfer exh ibits a weak (algebraic) distance dependence, i. e. k proportional to Nrl w ith eta = 1.7+/-0.2. This result supports that long-range hole migration in mixed DNA strands is a multistep hopping process between G bases.