Holmium laser resection nu transurethral resection of the prostate: Results of a randomized trial with 2 years of follow-up

Background and Purpose: The holmium laser (2140 nm) can be used to ablate, resect, and enucleate the enlarged prostate. The 2-year results of a random ized trial comparing holmium laser resection of the prostate (HoLRP) and tr ansurethral resection (TURP) are presented. Patients and Methods: The 120 patients were randomized to either TURF (N = 59) or HoLRP (N = 61), The patients were reviewed at 1, 3, 6, 12, 18, and 2 4 months postoperatively. Eighty six (72%) of the patients were available f or review at the 2-year mark. Results: At 2 years, there was no significant difference between the two gr oups in AUA Symptom Score, peak flow rate (Q(max)) value, or quality of lif e score, Adverse events, including reoperations, incontinence, and loss of erectile potency, were also similar. Conclusions: The HoLRP and TURF procedures result in similar clinical outco mes at 2 years.