Influence of biologically relevant ligands on oxidation of reduced glucoseoxidase by electrochemically generated [Ru-III(bpy)(2)XY] complexes

Authors
Ryabova, ES Csoregi, E Ryabov, AD
Citation
Es. Ryabova et al., Influence of biologically relevant ligands on oxidation of reduced glucoseoxidase by electrochemically generated [Ru-III(bpy)(2)XY] complexes, J MOL CAT B, 11(2-3), 2000, pp. 139-145
Citations number
20
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
ISSN journal
13811177 → ACNP
Volume
11
Issue
2-3
Year of publication
2000
Pages
139 - 145
Database
ISI
SICI code
1381-1177(200012)11:2-3<139:IOBRLO>2.0.ZU;2-#
Abstract
Complex formation between cis-[Ru(bpy)(2)(H2O)(2)](2+) (bpy = 2,2'-bipyridy l) and some biologically relevant ligands (pyridines, imidazole, histidines ) increases the rate constant for the oxidation of reduced glucose oxidase (generated in situ by D-glucose from the native enzyme) by the correspondin g Ru-III derivatives generated electrochemically. Almost a 20-fold rate acc eleration is demonstrated by the cyclic voltammetry for histidine as ligand , the rate constant being ca. 10(6) M-1 s(-1) at pH 7 (0.1 M phosphate). (C ) 2000 Elsevier Science B.V. All rights reserved.