The enigmatic inflammatory pseudotumours: the current state of our understanding, or misunderstanding

The inflammatory pseudotumour is a bona fide tumour in the sense of a mass lesion, which is known to present in virtually every anatomic region and or gan from the central nervous system to the gastrointestinal tract. A fundam ental question about pathogenesis is whether the inflammatory pseudotumour is a pseudo-or true neoplasm. There is evidence to support the argument tha t some of these fibroinflammatory masses are infection-associated and are o ften characterized by a proliferation of spindled histiocytes and/or dendri tic cells, in contrast to a myofibroblastic proliferation in the other infl ammatory pseudotumour, also known as the inflammatory myofibroblastic tumou r. Copyright (C) 2000 John Wiley & Sons, Ltd.