This article is a review of the history of the string galvanometer and of t
he electrocardiogram (ECG) on the occasion of the centennial of the instrum
ent. Einthoven most likely developed the string galvanometer prior to 1901,
the date of the first publication. The galvanometer made electrocardiograp
hy practical creating a new branch of medicine and even a new industry. In
1791 Galvani, in 1842 Mateucci and in 1855 Kolliker and Muller recorded, us
ing the nerve muscle preparation, contraction of injured muscle, contractio
n of muscle when laid across a beating heart, and occasionally two contract
ions. In 1872 Lippmann introduced the capillary manometer. Using the capill
ary manometer Waller recorded for the first time from body surface Voltage
changes generated by the heart. Einthoven and Lewis dominated the early yea
rs of electrocardiography. The former made his contributions by 1913 while
Lewis continued the studies of arrhythmias until 1920. The period following
1920 was influenced largely by Wilson. None did as much to advance ECG kno
wledge as did Wilson. The interest shifted to the theory of the EGG, abnorm
alities of wave form and of ECG leads. A major contribution of the ECG is i
n evaluation of ischemic heart disease and cardiac arrhythmias. Issues faci
ng electrocardiography in the year 2000 include a shortage of experienced e
lectrocardiographers, the advent of new noninvasive procedures and, paradox
ically, wide acceptance of the ECG by the medical profession. The role of t
he computer in analysis of the clinical ECG is limited. The technique, whil
e reasonably reliable for analysis of the normal tracing and some ECG wavef
orms, has serious limitations when applied to arrhythmias. The early hopes
for "stand-alone" programs are yet to be realized. (C) 2000 by the American
College of Cardiology.