M. Guillon et al., PREOCULAR TEAR FILM CHARACTERISTICS OF NONWEARERS AND SOFT CONTACT-LENS WEARERS, Optometry and vision science, 74(5), 1997, pp. 273-279
The aims of the current investigation were to: (1) characterize (struc
ture, volume, and stability) the preocular tear film of contact lens w
earers and nonwearers and (2) test for any difference between contact
lens wearers and nonwearers and between symptomatic and asymptomatic s
ubjects. The tear film structure and stability were tested using the T
earscope in conjunction with the biomicroscope observation system. The
tear prism height, which is indicative of the tear volume, was measur
ed with the slitlamp. The study was carried out on 239 subjects (478 e
yes) who attended our clinic for contact lens fitting. Of these, 184 w
ere habitual daily soft contact lens wearers who had not been wearing
contact lenses for at least 24 h; the other 55 were noncontact lens we
arers. The results obtained showed that: (i) the stability of the tear
film was correlated for two eyes of the same subject; (2) the structu
re, volume, and stability of the preocular tear film were similar for
both groups; (3) no difference in tear film stability was found betwee
n asymptomatic and symptomatic contact lens wearers, but a significant
difference was found between asymptomatic and symptomatic noncontact
lens wearers; and (4) the stability of the tear film was influenced by
the nature of the lipid layer present at the surface of the aqueous l
ayer; the greatest stability was achieved when the lipid layer was thi
ck and homogeneous (amorphous pattern).