Y. Fu et al., Sarcomatoid hepatocellular carcinoma with chondroid variant: Case report with immunohistochemical findings, PATHOL INT, 50(11), 2000, pp. 919-922
A case of sarcomatoid hepatocellular carcinoma (HCC) with a chondroid varia
nt in a 72-year-old woman is reported. Histologically, the tumor consisted
of typical HCC of adult type, with an adenocarcinoma-like structure and a s
arcomatoid component containing multinodular chondroid foci. Transition fro
m carcinoma to sarcomatoid component was observed. The cells containing muc
us were extremely few in adenocarcinoma-like structures. Immunohistochemica
lly, other than typical HCC, some of the chondroid cells, adenocarcinoma-li
ke cells and sarcomatoid cells were positive for alpha-fetoprotein.