A calcifying fibroma of the meninges - Report of a case and review of the literature

Citation
K. Ceyhan et al., A calcifying fibroma of the meninges - Report of a case and review of the literature, PATH RES PR, 196(11), 2000, pp. 747-752
Citations number
37
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
PATHOLOGY RESEARCH AND PRACTICE
ISSN journal
03440338 → ACNP
Volume
196
Issue
11
Year of publication
2000
Pages
747 - 752
Database
ISI
SICI code
0344-0338(2000)196:11<747:ACFOTM>2.0.ZU;2-O
Abstract
We report an unusual tumor related to the meninges designated as a calcifyi ng fibroma of the meninges. Our patient was a 44-year-old man. The tumor wa s located in the right frontotemporoparieta1 region and was excised totally via a right frontotemporoparieta1 craniotomy. The patient had recovered co mpletely, and no recurrence was observed in a follow-up period of three yea rs. Histopathologically, we noted scattered spindle cells among the hyalini zed collagenous stroma, dystrophic-psammomatous calcifications, abundant pe rivascular hyalinization and cartilagenous metaplasia. Immunohistochemicall y, the tumor cells showed actin, smooth muscle and vimentin immunoreactivit ies. Ultrastructurally, spindle cells showed fibroblastic features. The lesion is a true tumor and it should be kept in mind in the differentia l diagnoss of meningeal calcifying lesions.