This is a case report of a testicular papillary serous carcinoma of ovarian
type (PSCOT) diagnosed in a 50-year-old man. The tumor presented in the fo
rm of multiple papillary exophytic excrescencies on the visceral tunica vag
inalis testis lining the inner surface of a hydrocele sac. The tumor was hi
stologically a papillary serous carcinoma with numerous psammoma bodies, in
distinguishable from similar tumors arising on the surface of the ovary. Fo
llowing the tumor's surgical removal, the patient was treated with the same
drugs used to treat ovarian serous carcinomas, and he is alive two years a
fter the initial diagnosis. PSCOT must be distinguished from mesothelioma o
f the tunica vaginalis testis, a tumor with a most unfavorable prognosis. A
s shown here, immunohistochemical findings can be useful for formulating th
e correct diagnosis of PSCOT.