Phosphine-phosphite, a new class of auxiliaries in highly active and enantioselective hydrogenation

Authors
Pamies, O Dieguez, M Net, G Ruiz, A Claver, C
Citation
O. Pamies et al., Phosphine-phosphite, a new class of auxiliaries in highly active and enantioselective hydrogenation, PHYS CHEM P, 2(23), 2000, pp. 2383-2384
Citations number
26
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
ISSN journal
14639076 → ACNP
Volume
2
Issue
23
Year of publication
2000
Pages
2383 - 2384
Database
ISI
SICI code
1463-9076(2000)2:23<2383:PANCOA>2.0.ZU;2-2
Abstract
Excellent enantioselectivities (ee > 99%) and good activities (TOF > 1200 h (-1)) are achieved under mild reaction conditions in the Rh-catalyzed hydro genation of alpha,beta -unsaturated carboxylic acid derivatives with the fi rst family of phosphine-phosphite ligands containing a sugar backbone; thes e ligands are better than their diphosphine, diphosphite and phosphinite an alogues.