B. Holmstrom et Ew. Grimsley, Necrotizing fasciitis and toxic shock-like syndrome caused by group B streptococcus, SOUTH MED J, 93(11), 2000, pp. 1096-1098
A recent increase in reports of necrotizing fasciitis resulting from group
B streptococcus has alerted physicians to a possible concomitant increase o
f toxic shock-like syndrome. We report the second case of group B streptoco
ccus causing necrotizing fasciitis and toxic shock-like syndrome. A black w
oman, aged 52 years, with newly diagnosed diabetes mellitus had necrotizing
fasciitis type II of the left groin. Hypotension, elevated bilirubin and l
iver enzymes, and adult respiratory distress syndrome rapidly developed, Be
cause group B streptococcus was isolated from a normally sterile site, the
patient's condition met the criteria for toxic shock-like syndrome. Extensi
ve surgical debridement, hyperbaric oxygen therapy and intravenous antibiot
ic therapy (including clindamycin) were required for complete recovery. The
antitoxin effects of hyperbaric oxygen therapy and clindamycin should be f
urther investigated for the treatment of such patients.