P. Nemes et al., Cyclocondensation of beta-enaminonitriles, carbonyl compounds and acetonitrile. An effective route to various six-membered lactams, SYNLETT, (9), 2000, pp. 1327-1329
A cyclocondensation of beta -enaminonitriles, carbonyl compounds and aceton
itrile is described. Using different cyclic or open chain enaminonitriles v
arious N-heterocycles were obtained in a one-step procedure. The base catal
ysed reaction was also carried out with alpha,beta -unsaturated nitriles un
der similar conditions.