Cyclocondensation of beta-enaminonitriles, carbonyl compounds and acetonitrile. An effective route to various six-membered lactams

Citation
P. Nemes et al., Cyclocondensation of beta-enaminonitriles, carbonyl compounds and acetonitrile. An effective route to various six-membered lactams, SYNLETT, (9), 2000, pp. 1327-1329
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
9
Year of publication
2000
Pages
1327 - 1329
Database
ISI
SICI code
0936-5214(200009):9<1327:COBCCA>2.0.ZU;2-3
Abstract
A cyclocondensation of beta -enaminonitriles, carbonyl compounds and aceton itrile is described. Using different cyclic or open chain enaminonitriles v arious N-heterocycles were obtained in a one-step procedure. The base catal ysed reaction was also carried out with alpha,beta -unsaturated nitriles un der similar conditions.