Asymmetric Strecker route toward the synthesis of the Corey intermediate of lactacystin

Authors
Iwama, S Gao, WG Shinada, T Ohfune, Y
Citation
S. Iwama et al., Asymmetric Strecker route toward the synthesis of the Corey intermediate of lactacystin, SYNLETT, (11), 2000, pp. 1631-1633
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
11
Year of publication
2000
Pages
1631 - 1633
Database
ISI
SICI code
0936-5214(200011):11<1631:ASRTTS>2.0.ZU;2-B
Abstract
An efficient synthesis of Corey's precursor (2) of lactacystin has been acc omplished by the use of asymmetric Strecker synthesis of alpha -acyloxyketo ne 4 having L-Phe as a chirality transferring group.