Total synthesis of (S)-anabasine and (S)-anatabine

Authors
Felpin, FX Vo-Thanh, G Robins, RJ Villieras, J Lebreton, J
Citation
Fx. Felpin et al., Total synthesis of (S)-anabasine and (S)-anatabine, SYNLETT, (11), 2000, pp. 1646-1648
Citations number
29
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
11
Year of publication
2000
Pages
1646 - 1648
Database
ISI
SICI code
0936-5214(200011):11<1646:TSO(A(>2.0.ZU;2-Z
Abstract
A chiral synthesis of (S)-anabasine and (S)-anatabine from 3-pyridinecarbox aldehyde, via a ring closing metathesis reaction (RCM) as the key step, is reported in 8 steps for both products with overall yields of 35% and 30%, r espectively.