Synthetic studies on azadirachtin: An efficient asymmetric synthesis of the highly functionalized tricyclic decalin part of azadirachtin

Authors
Yamamoto, Y Ishihara, J Kanoh, N Murai, A
Citation
Y. Yamamoto et al., Synthetic studies on azadirachtin: An efficient asymmetric synthesis of the highly functionalized tricyclic decalin part of azadirachtin, SYNTHESIS-S, (13), 2000, pp. 1894-1906
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
13
Year of publication
2000
Pages
1894 - 1906
Database
ISI
SICI code
0039-7881(200011):13<1894:SSOAAE>2.0.ZU;2-#
Abstract
The detailed examination of intramolecular Diels-Alder reactions of several structurally related trienes led to construction of the desired tricyclic decalin moiety of azadirachtin with the alpha -hydroxyl groups at C1 and C3 as well as the oxygenated substituent at C8 in the naturally occurring for m in good yields.