Electrophilic amination of ketone enolates mediated by the DiTOX asymmetric building block: Enantioselective formal synthesis of alpha-aminoacids

Authors
Page, PCB McKenzie, MJ Allin, SM Buckle, DR
Citation
Pcb. Page et al., Electrophilic amination of ketone enolates mediated by the DiTOX asymmetric building block: Enantioselective formal synthesis of alpha-aminoacids, TETRAHEDRON, 56(49), 2000, pp. 9683-9695
Citations number
59
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
49
Year of publication
2000
Pages
9683 - 9695
Database
ISI
SICI code
0040-4020(200012)56:49<9683:EAOKEM>2.0.ZU;2-8
Abstract
Diastereoselective electrophilic amination of enolates derived from 2-acyl- 1,3-dithiane 1-oxides is used as the key step for an enantioselective synth esis of two alpha -hydrazido carboxylic acids, well-known precursors of alp ha -amino acids. (C) 2000 Elsevier Science Ltd. All rights reserved.