Facile chromium carbene mediated synthesis of functionalised 5-to 7-ring lactones

Citation
Gm. Good et al., Facile chromium carbene mediated synthesis of functionalised 5-to 7-ring lactones, TETRAHEDR L, 41(48), 2000, pp. 9323-9326
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
48
Year of publication
2000
Pages
9323 - 9326
Database
ISI
SICI code
0040-4039(20001125)41:48<9323:FCCMSO>2.0.ZU;2-U
Abstract
The reaction of pentacarbonyl[methoxy(2,6-dimethoxyphenyl)methylene]chromiu m(0) with acetylenic alcohols has been investigated. Reaction protocols hav e been optimised for rapid and direct access to functionalised gamma-, delt a-, and epsilon -lactone products possessing enol ether (i.e. masked carbon yl) functionality. (C) 2000 Elsevier Science Ltd. All rights reserved.