Aryl radical cyclisation onto pyrroles: a divergent synthesis of spiropyrrolidinyloxindoles and pyrroloquinolines

Authors
Escolano, C Jones, K
Citation
C. Escolano et K. Jones, Aryl radical cyclisation onto pyrroles: a divergent synthesis of spiropyrrolidinyloxindoles and pyrroloquinolines, TETRAHEDR L, 41(46), 2000, pp. 8951-8955
Citations number
31
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
46
Year of publication
2000
Pages
8951 - 8955
Database
ISI
SICI code
0040-4039(20001111)41:46<8951:ARCOPA>2.0.ZU;2-1
Abstract
The regiochemistry of cyclisation of an aryl radical on to a pyrrole is sho wn to depend on the N-substituent of the pyrrole. Changing this substituent allows the selective synthesis of either the spiropyrrolidinyloxindole or the pyrrolo[3,2-c]quinoline skeleton. (C) 2000 Elsevier Science Ltd. All ri ghts reserved.