Retrospective study of porcine circovirus 2 infection in Japan: Seven cases in 1989

Citation
M. Mori et al., Retrospective study of porcine circovirus 2 infection in Japan: Seven cases in 1989, VET PATH, 37(6), 2000, pp. 667-669
Citations number
14
Categorie Soggetti
Veterinary Medicine/Animal Health","Medical Research Diagnosis & Treatment
Journal title
VETERINARY PATHOLOGY
ISSN journal
03009858 → ACNP
Volume
37
Issue
6
Year of publication
2000
Pages
667 - 669
Database
ISI
SICI code
0300-9858(200011)37:6<667:RSOPC2>2.0.ZU;2-7
Abstract
Retrospectively, we demonstrated that seven pigs necropsied in 1989 had cha racteristic porcine circovirus 2 (PCV-2) lymphoid tissue lesions of severe lymphoid depletion, syncytial giant cell formation, and intracytoplasmic in clusion bodies in macrophages. Immunohistochemically, PCV-2 antigen was det ected in these tissues and the distribution of positive staining correspond ed to the distribution of inclusion bodies. Electron microscopy demonstrate d viral particles compatible with porcine PCV-2. Therefore, the disease occ urred in Japan as early as 1989.