Hodgkin's disease in a patient with von Hippel-Landau disease. A case report

Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited disorder with a predisposition to develop a wide variety of lesions: retinal, cereb ellar, spinal and medullar hemangioblastomas, renal cell carcinomas, phaeoc hromocytomas, and renal, pancreatic and epididymal cysts are the most frequ ent manifestations of the disease. The prevalence of VHL disease has been e stimated to be I per 36.000 persons. We report the case of a 68-year-old woman with Von Hippie-Lindau disease wh o developed high fever with pulmonary and hepatic lesions proven to be Hodg kin's disease on biopsy. To our knowledge, this is the first report of Hodgkin's disease in a patien t with Von Hippel-Lindau.