Management of hyperinsulinism in infancy and childhood

Hyperinsulinism (HI) in infancy presents a formidable challenge for the pae diatrician as it is one of the most difficult problems to manage in contemp orary paediatric endocrinology. Although there have been major advances in understanding the condition over the last five years, the neurological outc ome remains poor choice, and the choice of treatments continue to be unsati sfactory. This review article updates the management of HI derived from a C onsensus Workshop held by the European Network for Research into Hyperinsul inism (ENRHI) in 1999.