Randomised controlled trial of non-directive counselling, cognitive-behaviour therapy, and usual general practitioner care for patients with depression. I: Clinical effectiveness
E. Ward et al., Randomised controlled trial of non-directive counselling, cognitive-behaviour therapy, and usual general practitioner care for patients with depression. I: Clinical effectiveness, BR MED J, 321(7273), 2000, pp. 1383-1388
Citations number
25
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Objective To compare the clinical effectiveness of general practitioner car
e and two general practice based psychological therapies for depressed pati
ents.
Design Prospective, controlled trial with randomised and patient preference
allocation arms.
Setting General practices in London and greater Manchester.
Participants 464 of 627 patients presenting with depression or mixed anxiet
y and depression were suitable for inclusion.
Interventions Usual general practitioner care or up to 12 sessions of non-d
irective counselling or cognitive-behaviour therapy provided by therapists.
Main outcome measures Beck depression inventory scores, other psychiatric s
ymptoms, social functioning, and satisfaction with treatment measured at ba
seline and at 4 and 12 months.
Results 197 patients were randomly assigned to treatment, 137 chose their t
reatment, and 130 were randomised only between the two psychological therap
ies. All groups improved significantly over time. At four months, patients
randomised to non-directive counselling or cognitive-behaviour therapy impr
oved more in terms of the Beck depression inventory (mean (SD) scores 12.9
(9.3) and 14.3 (10.8) respectively) than those randomised to usual general
practitioner care (18.3 (12.4)). However, there was no significant differen
ce between the two therapies. There were no significant differences between
the three treatment groups at 12 months (Beck depression scores 11.8 (9.6)
, 11.4 (10.8), and 12.1(10.3) for non-directive counselling, cognitive-beha
viour therapy, and general practitioner care).
Conclusions Psychological therapy was a more effective treatment for depres
sion than usual general practitioner care in the short term, but after one
year there was no difference in outcome.