Effect of clinoptilolite on performance of broiler chickens during experimental aflatoxicosis

1. The amelioration of aflatoxicosis in broiler chickens was examined by fe eding 2 concentrations of natural zeolite (clinoptilolite). Clinoptilolite (CLI), incorporated into the diet at 15 and 25 g/kg, was evaluated for its ability to reduce the deleterious effects of 25 mg total anatoxin (AF; 76.4 0% AFB(1), 16.12% AFB(2), 6.01% AFG(1) and 1.47% AFG in diet on growing bro iler chicks from I to 21 d of age. A total of 360 broiler chicks were divid ed into 6 treatment groups (6 replicates of 10 broilers each): control, AF. CLI (15 g/kg), AF plus CLI (15 g/kg), CLI (25 g/kg), and AF plus CLI (25 g /kg). 2. Compared to controls, the AF treatment had significantly decreased body weight gain From week 1 onwards. The adverse effect of AF on food consumpti on (8.0%) and food conversion ratio (8.3%) was also shown over the entire 2 1-d Feeding period. 3. The addition of CLI (15 g/kg) to an AF-containing diet significantly red uced the deleterious effects of AF on food consumption and body weight gain . Food conversion ratio was also slightly improved by adding CLI (15 g/kg) to AF-containing diets. Food consumption, body weight gain and food convers ion ratio values were rendered numerically intermediate between AF and cont rol groups by the addition of CI,I (25 g/kg) to the AF-containing diet. 4. The addition of CLI (both 15 and 25 g/kg) to the AF-free diet did not pr oduce any significant changes compared with the controls, except for decrea sed total food consumption in the CLI (25 g/kg)-alone group. 5. These results suggest that CLI (15 g/kg) addition effectively diminished the detrimental effects of AF on the values investigated. Also, the lower dietary concentration of CLI (15 g/kg) was more effective than the greater concentration against the adverse effects of AF on the variables investigat ed in this study.