Synthesis of driman-8 alpha,11-diol from sclareol through 8 alpha,12-epoxy-14,15-bisnorlabdan-13-one

Authors
Aryku, AN Vlad, PF
Citation
An. Aryku et Pf. Vlad, Synthesis of driman-8 alpha,11-diol from sclareol through 8 alpha,12-epoxy-14,15-bisnorlabdan-13-one, CHEM NAT CO, 36(2), 2000, pp. 156-158
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
CHEMISTRY OF NATURAL COMPOUNDS
ISSN journal
00093130 → ACNP
Volume
36
Issue
2
Year of publication
2000
Pages
156 - 158
Database
ISI
SICI code
0009-3130(200003/04)36:2<156:SODAFS>2.0.ZU;2-7
Abstract
A four-step synthesis of driman-8 alpha: 11-diol from sclareol in 44% total yield is described that includes the intermediates (12R)-8 alpha: 12-epoxy -14, 15-bisnorlabdan-13-one, (12S)-8 alpha: 12-epoxy-12-acetoxy-13, 14, 15, 16-tetranorlabdane and 8 alpha :12-epoxy-13, 14,15, 16-tetranorlabd-11-ene.