M. Yoshikawa et al., Two cases of pediatric bone disease (eosinophilic granuloma and Brodie's abscess) showing similar scintigraphic and radiographic findings, CLIN NUCL M, 25(12), 2000, pp. 986-990
Two 9-year-old patients with femoral bone lesions were referred to the auth
ors' institution within a few days of each other. Both showed similar radio
graphic, magnetic resonance imaging, and scintigraphic findings. The radiog
raphs showed osteolytic lesions in the right femoral diaphyses, and gadolin
ium-DTPA-enhanced magnetic resonance imaging revealed inhomogeneous enhance
ment. Tc-99m HMDP showed marked linear accumulation with relatively low cen
tral uptake in the right femoral shafts, and TI-201 scintigraphy showed con
siderable uptake corresponding to the area seen with Tc-99m HMDP. Histologi
c analysis confirmed eosinophilic granuloma in the first patient and Brodie
's abscess in the second. The radiographic and scintigraphic findings in Br
odie's abscess may be similar to those in eosinophilic granuloma.