Two children with juvenile dermatomyositis and extensive, debilitating soft
tissue calcifications are described. Whole-body bone scans with Tc-99m MDP
were performed in both cases before and during specific treatment for the
calcinosis. Baseline studies showed marked tracer localization in the soft
tissues and provided an objective baseline assessment of the extent of the
soft tissue calcifications. Follow-up studies showed gradual clearance of t
he extraskeletal uptake and were useful in monitoring the therapeutic respo
nse. These cases show that skeletal scintigraphy can function as a useful a
uxiliary tool to evaluate calcinosis in children with juvenile dermatomyosi
tis.