Tests have become available that not only give an index of iron stores and
availability but also provide an integrated assessment of the efficacy of i
ts utilization. This has allowed the revision of previously accepted criter
ia of iron deficiency as well as the most appropriate strategies for iron a
dministration. By optimizing the response to erythropoietin, target haemogl
obin levels may be reached with smaller doses, resulting in substantial sav
ings. Curr Opin Nephrol Hypertens 9:669-674. (C) 2000 Lippincott Williams &
Wilkins.