Use of a fluoride ion selective electrode as a tool for monitoring relatively fast kinetic processes. Applications to the hydrolysis of organofluorophosphorus esters and 2,4-dinitrofluorobenzene
G. Moutiers et al., Use of a fluoride ion selective electrode as a tool for monitoring relatively fast kinetic processes. Applications to the hydrolysis of organofluorophosphorus esters and 2,4-dinitrofluorobenzene, ELECTROANAL, 12(17), 2000, pp. 1403-1407
Experimental conditions have been designed which allowed the use of a fluor
ide ion selective electrode for the monitoring of reactions that proceed wi
th a moderately fast departure of F- ion, i.e., t(1/2) approximate to 30 se
conds, in aqueous solution. The procedure applied in particular to the S(N)
A(R) substitution of 1-fluoro-2,4-dinitrobenzene with p-chlorophenoxide ion
and to the hydrolysis, catalyzed by oximate ions, of three organofluoropho
sphorus esters, namely sarin, soman and diisopropylphosphorofluoridate (DFP
). Depending upon the system at hand, the required buffering of the solutio
ns can be made up from the nucleophile reagent itself or through the use of
an external buffer.