Study on adsorption and oxidation of calf thymus DNA at glassy carbon electrode

The oxidation and adsorption of the temperature-denatured DNA at GC electro de are studied by differential pulse voltammetry and in situ FTIR spectroel ectrochemistry. The temperature-denatured DNA is adsorbed and formed a DNA multilayer at electrode surface. The temperature-denatured DNA showing part ly reversible process was first observed based on the reduction peaks appea ring at negative scans and the reversible spectral change. The oxidation pr oduct of the temperature-denatured DNA can not diffuse away from the electr ode surface easily due to the impediment of the DNA multilayer, so it can b e partly reduced.