Acute Myelomonocytic Leukaemia with Pseudo-Chediak-Higashi inclusions in leukaemic blasts report of an unusual case

Giant inclusions in the blast cells resembling that of Chediak-Higashi synd rome have been reported only in a handful of cases with acute leukaemia. Th ere is a paucity of data on the ultrastructural appearance of such unique l ight microscopic findings. As many of such patients were reported in late s eventies and early eighties [1-4] the outcome of treatment using present da y multiple induction/consolidation regimens in such patients has also been rarely reported due to the rarity of such patients. We report here on a patient with acute myeloid leukaemia showing pseudo-Che diak-Higashi inclusions in leukaemic blasts with unusual ultrastructural mo rphology.